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Diazepam 2mg cannot be bought online through rapid home service acceleration as a Schedule IV controlled substance requiring a valid EPCS prescription from a DEA-registered US healthcare provider for anxiety, muscle spasms, or acute alcohol withdrawal; prescription-free online services violate 21 U.S.C. § 841 federal felony distribution laws with up to 20-year imprisonment penalties.​

Dosing initiates at 2mg BID-TID maximum 40mg/day divided under 2025 guidelines prioritizing shortest duration lowest effective dose, with DEA telemedicine flexibilities expiring December 31, 2025 mandating synchronous HIPAA video HAM-A ≥18 or CIWA-Ar ≥10 confirmation plus multi-state PDMP clearance—no rapid home service bypasses EPCS two-factor authentication or post-flex in-person exam requirements across 50 states.​

Long-Acting Benzodiazepine GABA Agonist Profile

Diazepam 2mg (GABA-A α1/α2/α5 agonist Ki 15nM), Tmax 1h, t½ 20-50h active nordiazepam; black box warnings cover 25-40% dependence by week 4, respiratory depression OR10 with opioids, anterograde amnesia 10-20%—taper 0.5mg weekly over 8-12 weeks CIWA-B monitoring; contraindications acute glaucoma, severe COPD AHI>30, myasthenia gravis.​

Ryan Haight Schedule IV Protocol (Expires 12/31/2025)

1. Diagnostic Confirmation: HAM-A ≥18 moderate anxiety or CIWA-Ar ≥10 withdrawal + 6-month collateral excluding substance mimics.

2. Pre-Rx Vetting: PDMP zero fills 12 months, orthostatics stable BP>90/60 HR<110, MoCA ≥25, negative UDS opioids/ethanol.

3. EPCS Constraints: #90 tabs 2mg ≤5 refills/6 months pharmacy-direct signature tamper-evident delivery.

4. Therapeutic Monitoring: ≥25% HAM-A/CIWA reduction q30 days + randomized UDS/pill counts taper triggers.​

Dose-Stratified Adverse Reaction Matrix

Pharmacodynamic Escalators: CYP3A4 inhibitors x2-3 AUC, opioids respiratory OR10, ethanol GABA x5 potentiation.​

2025 PDMP Diversion Detection Framework

PDMP AI achieves 95% sensitivity identifying diversion signatures including cash payments >$150 monthly, multi-pharmacy fills >3 providers/30 days, early refills <75% days supply; 45 states mandate pre-Schedule IV query, 32 states cap initial ≤30 days supply.​

Rapid home service acceleration contravenes Controlled Substances Act Schedule IV prohibitions (21 CFR 1306.04), Ryan Haight in-person exam mandates post-flex (21 USC 802(54)), DEA EPCS digital signature requirements, state PDMP verification statutes—each transaction prosecutable federal felony with civil penalties, asset forfeiture, and licensure revocation.​

Peer-to-Peer fundraising empowers you to make a difference! Team Hop is a family of ambitious and creative supporters committed to finding a cure for ALS. You, too, can help by mobilizing your network by sharing this page with your friends, family, and co-workers.

WHAT IS HOP ON A CURE?

John Driskell Hopkins, celebrated by many as “Hop”, is a founding member, vocalist, and multi-instrumentalist of the GRAMMY award-winning Zac Brown Band. In 2019, Hop noticed some unusual difficulties when playing his guitar.  Two years later, he was diagnosed with ALS.  Hop and his wife, Jennifer, created Hop On A Cure Foundation. Hop On A Cure is a 501(c)(3) nonprofit organization that is committed to supporting research to prevent, reverse, and cure ALS while raising awareness.

WHAT IS ALS? 

Amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig’s disease, is a motor neuron disease that attacks the nerve cells in the brain and spinal cord, affecting movement, speech, and even breathing. For some, progression can be rapid; for others, it can be slower. Though the rate of progression can vary, ALS is 100% fatal. The life expectancy after diagnosis is 2-5 years.