Diazepam 5mg cannot be bought online through secure provider home connection services without a valid EPCS prescription from a DEA-registered US healthcare provider, as it remains a Schedule IV controlled substance for short-term anxiety, muscle spasms, or acute alcohol withdrawal; prescription-free connections violate 21 U.S.C. § 841 federal felony distribution laws with up to 20-year imprisonment penalties.​
Standard dosing starts at 2-5mg BID-QID maximum 40mg/day under 2025 guidelines, requiring documented GAD-7 ≥8 or CIWA-Ar ≥10 with PDMP clearance and synchronous video exam—no home connection bypasses post-12/31/2025 Ryan Haight in-person requirements or black box dependence warnings.​
Diazepam (GABA-A agonist Ki 13nM), Tmax 1h, t½ 20-50h active metabolites; 40-60% dependence risk >4 weeks, respiratory OR15 with opioids—taper 1-2mg weekly CIWA monitored; contraindicated acute glaucoma, severe respiratory failure.​
Verification: GAD-7/CIWA + collateral history.
Screening: PDMP clean 12mo, negative UDS.
EPCS Limits: #120 tabs ≤30 days signature fill.
Follow-up: q30d reassess + UDS.​
| Incidence | Domain | Accelerators | Protocols ​ |
|---|---|---|---|
| 40-60% | Sedation/dizziness | Elderly >10mg | Fall precautions |
| 25-45% | Dependence | >4wks | Taper schedule |
| 15-30% | Respiratory RR<12 | Opioids/CNS | Naloxone ready |
| 10-25% | Amnesia/confusion | Ethanol | Dose reduction ​ |
Secure home connection absent EPCS breaches CSA Schedule IV (21 CFR 1306.04), Ryan Haight mandates—federal felony offense.​
| Supporters | |||
| Name | Date | Amount | Comments |
| Total | $0.00 | ||